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  1. The Most Effective Smoking Cessation Tool-E Cigarettes

    The Most Effective Smoking Cessation Tool-E Cigarettes

    What's the best way to quit smoking? A new study shows that e-cigarettes are almost twice as efficient as other methods in helping people quit smoking, which significantly improves their health prospects. But many people don't even know the options and benefits of e-cigarettes. Although the department of public health has concluded that e-cigarettes can reduce the risk of smoking by up to 95 percent.  reference:https://www.gov.uk/government/news/e-cigarettes-around-95-less-harmful-than-tobacco-estimates-landmark-review smokers and non-smokers are not familiar with the difference between e-cigarettes and traditional smoking, and the harm which traditional smoking can cause. Both smoking and e-cigarettes are nicotine delivery systems. But conventional cigarettes burn tobacco, which causes thousands of chemicals to be inhaled during the release of nicotine. And it is burning and inhaling of these chemicals that cause cancer, not nicotine. Nicotine has not been linked to cancer or cardiovascular and lung disease. But it is an addictive substance that can be toxic or even life-threatening in excess. However, nicotine itself is not associated with an increase in cancer or any major disease. Nicotine also increases adrenaline, which can cause a faster heart rate and peak blood pressure, similar to the effect of drinking a cup of coffee. Is Nicotine The Most Dangerous Chemical In Tobacco? E-cigarettes are tobacco-free. Instead, the liquid is made of two FDA-approved safe substances, propylene glycol, and glycerin, which form steam when heated. These vapors are much less harmful than the gases produced by burning conventional cigarettes. E-cigarettes are more effective at helping people kick the habit than patches and chewing gum. Now doctors in the UK are encouraging current smokers to switch to e-cigarettes. The American cancer society also acknowledges that modern e-cigarettes are less harmful than traditional cigarettes, but the health effects of long-term use are unclear. There are some clinicians who recommend that some smokers do not try to quit or use FDA-approved smoking cessation drugs. These people should be encouraged to switch to the least likely tobacco products, like e-cigarettes, which is more effective than continuing using combustible quitting methods. E-cigarettes are about to become a way for New Zealand's government to recommend smoking cessation. After Saudi Arabia legalized e-cigarettes, Seychelles will become the first country to lift the ban. Although the benefits of e-cigarettes are more and more known and accepted, e-cigarettes are not completely harmless. They contain nicotine, which can affect the brain development of teenagers and is definitely addictive. Therefore, it is very necessary to ban the use of e-cigarettes by minors. Are e-cigarettes harmful? Can it help people quit smoking? Despite this, most countries are hesitant or resistant to e-cigarettes. The goal of those people who say no to vaping seems to be to prevent teenagers from smoking. But this should not be used as an excuse to ignore the enormous potential of e-cigarettes to improve the health of adult smokers. A man named Dan foster started using e-cigarettes 10 years ago. It says switching from cigarettes to e-cigarettes is not only cheaper but also appears to solve some health problems. "I used to get a really bad sinus infection every three months," says Dan Foster. "Now it's gone." More smokers reported breathing better and coughing less after using e-cigarettes. The e-liquid has different nicotine concentrations; Nicotine free to high. Dosage can be controlled according to personal preference, which can help slowly reduce nicotine dependence. What Does A Heavy Smoker Think Of E Cigarette The e-cigarette is still a controversial product, and its development path is still very long. We will wait and see how it will end up.  
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  2. What Are The Benefits Of Quitting Smoking?

    What Are The Benefits Of Quitting Smoking?

    What are the benefits of quitting smoking?   What are the benefits of quitting smoking? Smoke-free for 20 minutes: blood pressure, heart rate dropped to normal, hands and feet temperature increased to normal. Smoke-free for 8 hours: blood carbon monoxide concentration dropped to normal, blood oxygen concentration increased to normal. Smoke-free for 24 hours: fewer heart attacks. Smoke-free for 48 hours: smell and taste better. Smoke-free for 2 weeks to 3 months: improved circulation in the body, increased lung function by 30%, and easier walking. Smoke-free for 1-9 months: respiratory symptoms reduced, such as cough, phlegm, asthma, etc. Lung cilia regeneration, promote the function of sputum discharge and clearance; Reduce respiratory infections. Smoke-free for 1 year: reduced risk of cardiovascular disease by half. Smoke-free for 5 years: lung cancer mortality rate is half of a pack of cigarettes a day; The risk of oral, esophageal and laryngeal cancers was halved. Cerebrovascular disease is the same as non-smokers after 5-15 years. Smoke-free for 10 years: lung cancer mortality and non-smokers the same; Precancerous changes disappeared. The risk of cancers of the mouth, esophagus, larynx, bladder, kidney, and pancreas is reduced. Smoke-free for 20 years: the risk of cardiovascular disease is the same as that of non-smokers.   Why is it so hard to quit smoking? Physiological dependence Physiological dependence mainly refers to the body's desire for nicotine, nicotine is one of the main components of cigarettes, after smoking nicotine to the brain only 8 seconds, the brain caused by nicotine briefly increased alertness. Thus, although nicotine does not cause cancer directly, it is highly addictive. Chronic smokers are basically nicotine addicts. Their bodies must keep a certain amount of nicotine at any time. Once the concentration drops, unpleasant or unbearable symptoms will appear.   Psychological dependence Psychological dependence includes psychological or emotional factors, as well as special situations or occasions. Psychological or emotional factors such as tension, boredom, worry, excitement or joy are easy to make people think of smoking. Special scenes or occasions such as meditation, writing, getting up, after dinner, etc., will depend on smoking, and over time, it will become a habit, formed a part of life.   Social factors Social factors are a kind of external influence, such as mutual recognition and encouragement of smoking behavior in social activities, strong promotion by tobacco dealers, the transmission of wrong information about smoking by media, and influence of family members.   How can I quit smoking successfully? Before you do anything, you should make up your mind first. Quitting smoking is no exception. How can you make up your mind to quit smoking? You could look in the mirror to see your yellow skin, fingers, and teeth; look how much your body changed; Whether the family member does not want to be close to you; is your child imitating, And then tell yourself that you must make up your mind to quit smoking. After making up my mind to quit smoking, it’s also important to get other people’s help and supervision, asking your families to support encourage you. And for smoking as a habit, throw away anything which causes smoking desire, such as pipe, ashtray or lighter; Break the habit of fixed smoking, do not smoke after getting up or dinner; Avoid to go to smoking places, such as bars, KTV, karaoke, etc. Join a smoking cessation group, where you have a group of quitters around you and supervise each other. For life, it’s important to keep a regular schedule and do more exercise. And should not be too busy or tired. In this case, smoking impulse or reason will be avoided. The use of smoking cessation AIDS such as smoking cessation drugs, including natural plant smoke suppressant and anti-smoking element, helps you to be of aromatherapy, refreshing, regulating qi and opening collaterals. Through the way of breathing, under the dual effects of natural plant smokes in and no-smoking element, it can block the nicotine receptor, eliminate the dependence of smokers on nicotine, and solve the painful symptoms of quitting smoking. Chewing gum to counteract the craving for nicotine in the body of a smoker. E-cigarettes, as the world's most widely used nicotine replacement therapy, help reduce the amount of nicotine inhaled by smokers gradually. Generally from high to low, gradually lower. These are all practical AIDS. Seek special medical attention if necessary.                  
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  3. Is Nicotine The Most Dangerous Chemical In Tobacco?

    Is Nicotine The Most Dangerous Chemical In Tobacco?

    Is Nicotine The Most Dangerous Chemical In Tobacco? Like caffeine, nicotine is an alkaloid that plays an important role in the history of modern human civilization. It is one of many highly toxic alkaloids from the Solanaceae family. The main acute toxicity of nicotine is neurotoxicity, and the absorption pathway is extensive: the digestive tract and the respiratory tract nicotine will be absorbed quickly, and the excess will cause poisoning. The acute toxicity of the central nervous system(CNS) is headache, dizziness, headache, nausea, vomiting and even delirium, convulsion, and coma. The toxicity of the autonomic nervous system is manifested as abdominal pain, diarrhea, heart rhythm disorder, salivation, sweating, and blood pressure first increased and then decreased sharply. Accompanied by dyspnea, pupil constriction, limbs twitching, severe cases will appear bundle tremors and progressive muscle weakness. The direct cause of death of most people who are acutely poisoned by nicotine is respiratory failure caused by respiratory muscle paralysis. Nicotine influence: Cardiovascular changes Nicotine stimulates the production of adrenaline, which causes the heart to beat faster, raising blood pressure and tightening blood vessels. Adrenal stimulation Part of the reason for the pick-me-up is that smoking stimulates the release of adrenaline, making the central nervous system more active. Muscle tremors Because nicotine ACTS on the Ach(acetylcholine) receptor, which stimulates the sympathetic and parasympathetic nervous systems, and it causes skeletal muscle contractions and causes skeletal muscle contraction, coupled with a series of factors such as adrenaline release, can cause muscle tremors, such as hands will occur Some tiny jitters.   Digestion inhibition Nicotine inhibits digestion in the stomach and increases intestinal activity, reducing overall absorption of nutrients from food.   Feel pleasure This is mainly related to the increase in the secretion of DA (dopamine) by nicotine. Because DA is a neurotransmitter involved in reward-learning mechanisms, some people are more susceptible to cravings due to the secretion of DA and defects in certain receptor functions.   Depression Because nicotine will stimulate the secretion of DA, replacing the normal DA function. Therefore, if smokers stop smoking, they will be in a bad mood. Tar and carbon monoxide are more harmful. Whether the "most toxic" in cigarettes is nicotine is not good to say. In fact, carbon monoxide and tar were once considered to be the main culprit in cigarette harm. There is currently no conclusive evidence that nicotine can cause cancer, but there is evidence that nicotine can promote tumor development (cancer promoters, tumor promoters, Cardinale A, Nastrucci C, Cesario A, Russo P (January 2012). "flavor: Specific role in angiogenesis, proliferation, and apoptosis". Critical Reviews in Toxicology42 (1): 68 -- 89. At the same time, nicotine, because of its central role, is the source of cigarette addiction. Tobacco smoke contains more than 60 carcinogenic chemicals, the most harmful of which is tar and carbon monoxide. Tar contains about 5000 kinds of organic and inorganic chemicals that are the leading cause of cancer. Tobacco produces a tobacco-specific nitrosamine (TSNA) during fermentation and when ignited. Nitrosamines are extremely potent carcinogens. When carbon monoxide is smoked, the tobacco does not burn completely, so more co is produced. Carbon monoxide binds to hemoglobin, affects the blood oxygen supply to the cardiovascular system, promotes the increase of cholesterol, and indirectly affects the formation of certain tumors. The lungs contain tiny hairs that help remove foreign material to clean them. Hydrogen cyanide from cigarettes interferes with the lungs' scavenging system, causing toxic chemicals in the smoke to build up in the lungs. At the same time, highly reactive chemicals can damage the heart muscle and blood vessels, which react with cholesterol, causing the buildup of fatty substances in the artery walls that can lead to heart disease, stroke, and vascular disease.
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  4. Possible Mycotoxin Contamination In E-Cigarettes?

    Possible Mycotoxin Contamination In E-Cigarettes?

    Possible mycotoxin contamination in e-cigarettes? April 28, 2019 -- the Harvard School Of Public Health has published a research report on e-cigarettes, which pointed out that most of the e-cigarettes in the United States may be contaminated with mycotoxins. The team surveyed 75 popular brands of e-cigarettes in 2013 and found that 23 percent contained traces of endotoxin and 81 percent contained dextran. The report notes that endotoxins are present in gram-negative bacteria, which are found on most fungi, and that contact with humans can lead to health problems such as asthma, decreased lung function and inflammation, the researchers said. The report by Harvard was challenged by the American E-Cigarette Association. Gregory Conley, chairman of the American e-cigarette association's advocacy group, said the study should compare levels of toxins in e-cigarettes and cigarettes. Given that many smokers now mistakenly believe that e-cigarettes are as dangerous as cigarettes, Harvard without comparing electronic cigarettes in cigarette adequately published before the report is a disgrace, Gregory Conley, also points out the research focused on the 2013 best-selling brand, rather than the current brand, and there is no report also indicate the product or brand name.
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  5. Are e-cigarettes harmful? Can it help people quit smoking?

    Are e-cigarettes harmful? Can it help people quit smoking?

    Are e-cigarettes harmful? Can it help people quit smoking? The U.S. centers for disease control and Prevention (CDC) estimates that e-cigarette is still a new thing and that the health effects of long-term use are unknown. E-cigarettes often contain nicotine, which is harmful to fetal development and cognitive development in people under the age of 25. In addition to nicotine, vapors from e-cigarettes are not entirely harmless. They contain some tiny particles that may cause cancer, and may also contain some heavy metals and volatile compounds [15]. Some studies have also shown that e-cigarettes increase the risk of heart disease and cancer. Public health England (PHE) released a 113-page report in 2015 detailing the risks associated with e-cigarettes. The report concluded that e-cigarettes are 95percent safer than smoking and that policies should encourage the use of e-cigarettes as a key tobacco control strategy to reduce the harm caused by smoking. Note that "smokers" are encouraged to use e-cigarettes to help them quit smoking [6]. England's department of public health is sticking to its claim that e-cigarettes are 95percent safer than cigarettes in 2018, despite much skepticism. [17] In February 2018, the American cancer society (ACS) also issued a position statement: while the long-term effects of e-cigarette use are yet unknown, it can be estimated that e-cigarettes are less harmful than regular cigarettes. The association explicitly encourages people to try e-cigarettes as a smoking alternative. And the clinicians are also suggested to recommend e-cigarettes to smokers as an alternative to conventional cigarettes. It is for sure that e-cigarettes are only a transitional state, and quitting smoking should always be the first choice [9]. In November 2018, the centers for disease control and Prevention (CDC) made its case to the public. They suggest that smokers should start using an e-cigarette and trying to quit smoking by it. However, it also reminds us that e-cigarettes are not harmless. Teenagers and pregnant women, as well as non-smokers, should not try them because they are less harmful than cigarettes [15]. After weighing the pros and cons, public bodies in both the UK and the US tend to agree that e-cigarettes are still better for smokers than cigarettes. E-cigarettes may not help stop smoking Nicotine replacement products (NRT) are the generic term for a number of smoking-cessation products that are primarily used in nicotine replacement therapy (NRT). Nicotine in cigarettes is an addictive substance. When you quit smoking, you will have a withdrawal reaction. If nicotine patches, nicotine gum, or nicotine sprays are used to deliver nicotine to the blood during smoking cessation, the withdrawal response can be alleviated and the success rate of smoking cessation can be improved. In 1996, the world health organization (WHO) officially recommended nicotine replacement therapy to all countries. The FDA has also approved at least four legal nicotine replacement products to help people quit smoking. The same seems to be true for e-cigarettes, which the WHO, in fact, calls the "electronic nicotine delivery system" and looks at alongside other nicotine substitutes. But while e-cigarettes are similar to nicotine substitutes, they are also similar to smoking in terms of behavior, so you can't just assume that e-cigarettes will help you quit. Researches are inconsistent on whether e-cigarettes can help people quit smoking. For example, a 2014 paper published on JAMA showed no improvement in quit success and no reduction in cigarette consumption among e-cigarette users in a longitudinal analysis of 949 smokers who participated in a twice-yearly online survey. However, at the same time, the author of the paper also said that this survey relies on individual oral reports, and the respondents do not know enough about the usage, frequency, and habits of e-cigarettes [7]. Other studies have suggested that e-cigarettes can help smokers quit or reduce smoking. A meta-analysis study in 2016 showed that those who chose to quit smoking via e-cigarettes had a 28percent higher probability of successfully quitting smoking than those who did not choose e-cigarettes [9]. A recent study published in the Cochrane systematic review database found that e-cigarettes helped people quit smoking, and it works better than placebo [5]. Another 2015 meta-analysis showed that smokers were more likely to quit smoking with nicotine-containing nape than without. This suggests that to some extent e-cigarettes do work as well as traditional nicotine replacement therapy. This study even shows that e-cigarettes are more successful than traditional nicotine replacement therapy in getting people to quit smoking (20percent success rate vs 10percent success rate) [8]. The department of public health credits e-cigarettes with an overall decline in smoking rates from 2011 to 2017. In the UK, the situation is more optimistic. In 2018, the ministry of public health published a blog saying that e-cigarettes can help people quit smoking, at least in the UK. There are 2.9 million e-cigarette users in the UK, and more than half of it has given up smoking completely. And e-cigarettes are expected to help other 20,000 people quit each year. With the promotion of e-cigarettes, the smoking rate in Britain has been declining year by year, reaching a historical low of 15.5percent, which is only higher than Sweden in the whole of Europe [17]. To be conservative, according to WHO in 2014, the existing studies are not enough to prove that the use of e-cigarettes can help completely kick the habit of smoking, and the traditional nicotine therapy that has been proved to be effective is preferred [14]. WHO also believes that although quitting completely is hard, people can smoke and vape at the same time. Since they smokeless cigarettes, e-cigarettes can still be recommended to smokers [14]. Should e-cigarettes be banned Should we emphasize that e-cigarettes are 95percent less harmful than cigarettes, or should we emphasize that e-cigarettes are harmful? It's a dilemma for public health. If policies are biased toward promoting e-cigarettes as less harmful than cigarettes, then smokers are more likely to switch to e-cigarettes and cigarettes are less harmful. However, once teenagers know that e-cigarettes are less harmful, they may start vaping. It may even have increased smoking overall, which backfires. But just saying that e-cigarettes are harmful will cause smokers to distrust e-cigarettes and scare away smokers who want to change to e-cigarettes. In 2013, only 7 percent of Britons were under the mistaken belief that e-cigarettes were as bad as cigarettes, compared with 25 percent in 2018. The department of public health (moh) said that some of the comments focused too much on the dangers of e-cigarettes and ignored the comparison with cigarettes, which affected the public's correct understanding of the dangers of e-cigarettes and cigarettes. [16] In the dilemma mentioned above, the specific side to focus on varies from country to country The UK as a whole is inclined to support the promotion of e-cigarettes. The propaganda emphasizes that "e-cigarettes are less harmful than cigarettes", which can dispel smokers' doubts about the safety of e-cigarettes and emphasize the comparison between e-cigarettes and cigarettes. In December 2018, public health England (PHE) produced a short film, using cotton balls, to show people the difference between one month of smoking cigarettes and one month of e-cigarettes using [12]. Britain seems more optimistic about young people using e-cigarettes. For example: in January 2019, a charity called cancer research UK said there was a lack of evidence in the UK that e-cigarettes were leading teenagers to smoke. Young people's smoking rate has been declining, and the probability of non-smoking young people using e-cigarettes is very low, around 0-1percent [10]. The document further points out that in Europe, although young people are more willing to try e-cigarettes, young people end up using e-cigarettes less than older people, which indicates that trying e-cigarettes does not cause smoking [10]. In December 2018, the department of public health released a short film showing that e-cigarettes are less harmful than traditional cigarettes. Call on the Public not to choose to smoke rather than try e-cigarettes because of the false perception that e-cigarettes are as harmful as cigarettes There are more young people in the United States use e-cigarettes, so the US has a more cautious attitude toward e-cigarettes From 2017 to 2018, the percentage of high school students exposed to e-cigarettes soared from 11.7 percent to 20.8 percent, up as much as 78 percent, according to the national youth tobacco survey. The number of junior middle school students increased from 3.3percent to 4.9percent, which increased by 48percent. In one year, there were 1.5 million people. It is estimated that 3.6 million middle school students have been exposed to e-cigarettes. (contact counted as having tried e-cigarettes within 30 days of the survey) Both the material and the department of public health promo were released in December 2018, but different attitudes were expressed. This material emphasizes the conclusion that e-cigarettes are harmful, that e-cigarettes are not effective in quitting smoking, and that e-cigarettes are more likely to cause young people to smoke [6]. In a word, if you are a heavy smoker who has failed many times to quit smoking; e-cigarettes may be a choice to quit smoking. But if you've never smoked, don't try any e-cigarettes. At the same time, e-cigarettes are not completely harmless. It's just less harmful than cigarettes. There is a debate about whether e-cigarettes can help people to stop smoking. The resources [5]Hartmann‐Boyce, J., McRobbie, H., Bullen, C., Begh, R., L. F., & Hajek, P. (2016). Electronic cigarettes for smoking . The Cochrane Library. [6]McNeil, A., Brose, L. S., Calder, R., Hitchman, S. C., Hajek, P., & McRobbie, H. (2015). E-cigarettes: an evidence update. A report commissioned by Public Health England. Public Health England, 111. [7]Grana RA, Popova L, PM. A Analysis of Electronic Cigarette Use and Smoking . JAMA Intern Med. 2014;174(5):812–813. doi:10.1001/jamainternmed.2014.187 [8]Rahman, M. A., Hann, N., Wilson, A., Mnatzaganian, G., & Worrall-Carter, L. (2015). E-cigarettes and smoking : evidence from a systematic review and meta-analysis. PloS one, 10(3), e0122544. doi:10.1371/journal..0122544 [9]Kalkhoran, Sara; Glantz, Stanton A (2016). "E-cigarettes and smoking cessation in real-world and clinical settings: a systematic review and meta-analysis". The Medicine. 4 (2): 116–128. [10]cancer research UK [11]Youth Tobacco Use: Results from the National Youth Tobacco Survey [12]Smokefree ‘Health Harms’ – Impact of smoking vs vaping demonstration [14]electronic nicotine delivery systems report by WHO [15]About Electronic Cigarettes (E-Cigarettes) [16][17]Public health matters-GOV.UK
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  6. 2019 Research And Analysis: E Cig Can Improving Health In England

    2019 Research And Analysis: E Cig Can Improving Health In England

    2019 Research And Analysis: E Cig Can Improving Health In England Proof Summarize evidence to support UK e-cigarette policy and regulation. E-cigarettes or e-cigarettes system can play an important role in improving public health. Survey There has been a steady increase in experimentation on e-commerce in the UK in recent years. However, regular use remains low, with 1.7percent of 11 to 18-year-olds in the UK reporting using it at least once a week in 2018 (0.4percent of 11-year-olds and 2.6percent of 18-year-olds). E-cigarettes using is still associated with smoking. The percentage of young people who have never smoked using at least one e-cigarette per week remains low (just 0.2percent among 11 - to 18-year-olds in 2018). The percentage of non-smokers who have tried e-cigarettes is rising. Without e-cigarettes, it's unclear to what extent these young people would attempt to smoke. Policy changes The background to the report is that smoking remains the leading preventable cause of disease and premature death and one of the biggest causes of health inequality. As a result, the national institute for health and care excellence (NICE) has published guidelines for health and social care workers on how to conduct informed discussions on e-cigarettes. The Commons science and technology committee has published a report on the European Community, which includes recommendations on harm reduction, smoking cessation, the community's mental health environment, and regulation. Support The advertising commission (CAP) and the broadcasting commission (BCAP) announced that they would lift the European commission's blanket ban on making health claims in non-broadcast advertising. NHS England's long-term plan proposes a new universal smoking cessation service for long-term users of professional mental health and learning disability services. This would include the option for smokers to switch to e-cigarettes while in hospital. Quit practitioners and health professionals should provide behavioral support to smokers who wish to use e-cigarettes to assist them in quitting. Quit-smoking practitioners and health professionals who support smokers in quitting should receive education and training on the use of e-cigarettes in smoking cessation attempts. The national smoking cessation and training center (NCSCT) provides online training. The report was co-authored by four experts from the UK's top universities, King's College London and the University of Edinburgh. Reference material: Vaping in England: an evidence update February 2019 The article recommended:  What Does A Heavy Smoker Think Of E-Cigarette ;                                            4 Data Show That Vaping Is Safer Than Smoking;
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  7. What Are Other Things Like Nicotine?

    What Are Other Things Like Nicotine?

    What are other things like nicotine? Alkaloids are basic organic compounds containing nitrogen that exist in nature, especially in the plant kingdom. Most alkaloids have optical activity, and the properties of different optical isomers are obviously different. Most alkaloids have special biological activities and are the main active ingredients of most Chinese herbal and native medicines. The discovery and application of alkaloids may be a great achievement in the field of pharmaceutical chemistry. As modern organic synthesis has grown by leaps and bounds, alkaloids have become a source of new drugs. Now there are quite a number of common drugs, are natural alkaloids after the structural modification of the product. For example, many of the effective ingredients in the compound cold medicine ephedrine and so on of course, at the same time, toxic alkaloids are not in the minority, which is not a lack of very dangerous poison. Now let me introduce the poisonous alkaloids. 1. Caffeine: The systematic name for caffeine is 1,3, 7-trimethyl xanthine, also known as theobromine, and its direct biological source is coffee berries and tea. In fact, caffeine analogs are found in many plants, and quite a few of these plants are used by people all over the world to make drinks:   Caffeine is metabolized in the liver and its metabolites are theophylline, theobromine, and xanthine. These 3 look very similar, actually its pharmacological action also is basic and identical, it is a central stimulant. Small doses of caffeine act on the brain cortex high central, can make people excited, eliminate fatigue, and can improve thinking, sleep will also reduce. Caffeine also dilates bronchial tubes and diuretics. High doses of caffeine can cause some adverse effects. Because its central excitatory action can make the person feel so disgusting, have a headache or insomnia. Single high dose of caffeine or especially large doses of caffeinated beverages can cause anxiety, muscle tremors, tinnitus, palpitations, and convulsions. But it's only toxic n in large quantities, so small amounts of caffeine aren't harmful. 2. Morphine:   Morphine is the main ingredient of the exudate of poppy fruit, one of the first discovered alkaloids, and a central analgesic that is now tightly controlled in almost all countries.   The toxicity of morphine is mainly reflected in its addiction after repeated use. The acute death dose of morphine is around 250mg. If taken in excess, morphine can cause severe respiratory depression and can cause the death of respiratory paralysis if not rescued in time. 3. Colchicine Source of colchicine:   Colchicine is still used as a medicine to treat gout, but you need to be very careful about how you use it. It can also be used in chemotherapy for leukemia, skin cancer, and breast cancer. The maximum daily dose of colchicine should never exceed 6mg, and patients must get regular examinations of liver and kidney function and blood routine. If a patient develops a gastrointestinal reaction while taking colchicine, it could be a harbinger of serious poisoning. The acute toxic reaction of colchicine is complex and toxic to blood, gastrointestinal tract, heart, and urinary system. The biggest harm may be the inhibition of the respiratory center, if patients don’t get instant treatment after poisoning, the mortality rate is relatively high. And there is no specific antidote for acute colchicine poisoning. 4. Aconitine From the beautiful buttercup:   Aconitine is used in the adjuvant treatment of cancer now, mainly at reducing cancerous pain. Because it can paralytic peripheral nerve ending directly, producing a local analgesic effect. Only 0.2mg oral administration of aconitine will cause a toxic reaction, and the lethal dose is about 2mg-5mg. The effect is very rapid and violent. The main reaction is intense excitement of the center and direct action on the myocardium. 5. Scopolamine      When the amount of the tropane alkaloid is high, it affects the central nervous system. At first, there will be anxiety, talkativeness. Severe hallucinations, movement disorders, and convulsions may occur at doses that are toxic. 6. Solanine   In immature or sprouted Solanaceae plants, there is a sharp increase in the content of sobering.   The main toxicity of sobering is irritation and causticity of gastrointestinal mucosa and central paralysis. The reaction is severe stomach pain, nausea, vomiting and difficulty breathing. 7. Gelsemine   It’s a beautiful flower but very toxic too. The main toxic effect of hook-kiss is still neurotoxicity with the main respiratory depression as a symptom, and the cause of death is still respiratory paralysis. 8. Strychnine There are no beautiful flowers for Strychnine, but it looks very tasty. The seeds of strychnine are not only very bitter but also contain indole alkaloids which are highly toxic.   The mildly toxic effects of strychnine are facial muscle stiffness, a stiffness of the limbs, and adduction of the feet. At the same time, brucine can also make the respiratory muscle group rigid, then stop people’s breathing. The lethal dose of brucine is about 10mg. 9. Coniine What it looks like:   The most famous person in history who was poisoned by the celandine was Socrates. In ancient Greece, hemlock was often used as a component in the juice to kill people of high status, but it was also used for spasmolysis. Natural hemlock alkaloid is dextral that has special stink. The lethal dose ranged from 60 to 100mg, mainly due to neurotoxicity, paralysis of motor nerve endings and spinal cord. The victim shows weakness, slow breathing, and eventually death from respiratory arrest. 10. Nicotine Nicotine is an important component in tobacco leaves, colorless, odorless, transparent and volatile. It is toxic to aquatic organisms but highly insecticidal to insects. The main mechanism of action is still neurotoxicity, as a catalyst, it works through contact with the insect body surface. If people take in a large dose of it at one time, then he or she would eventually die of respiratory failure caused by paralysis of the respiratory muscles. 11. Tetrodotoxin Tetrodotoxin is characterized by rapid onset of poisoning, generally within 10 minutes or so after eating. The first symptom is numbness and tingling of the skin, then it quickly turns into a general paralysis of the muscles and a gastrointestinal reaction. Severe acute poisoning can result in paralysis of the respiratory muscles, or even decreased blood pressure and circulatory failure. Tetrodotoxin was once considered as the most toxic natural non-protein toxin, and there is no specific antidote for tetrodotoxin at home and abroad. But tetrodotoxin is degraded and excreted very quickly in the body, and most people recover from tetrodotoxin poisoning if it doesn't kill them within eight hours. – however, not many people can actually recover from it. By introducing these alkaloids, we are trying to let you know their toxicity. And as a manufacturer of tobacco products, we believe that it's our responsibility to tell you that our products Vladdin contain nicotine, which is a highly addictive substance. And it is not recommended to sell to non-smokers. What is nicotine salt, Does vladdin contains nicotine salt?
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  8. What Is Your Favorite E-Liquids?

    What Is Your Favorite E-Liquids?

    The blowout phenomenon of nicotine salt e-liquids has just emerged, and waves of new products have entered the user's field of vision. If the birth of e-cigarettes changed the fate of millions of smokers around the world, the emergence of nicotine salt e-liquids extended the selection for smokers. Different from traditional nicotine e-liquids, People will feel more comfortable inhalation and dispelling when used nicsalt e-juice. It is suitable for low-power equipment to achieve the advantages of quick addiction and small vapor without disturbing others. The development of nicotine salt smoke oil is rapid, and various methods of using tobacco for smoking and smoking cessation have prompted more targeted devices to be born. However, before this big classification is often not clearly popularized, novice players should pay attention to the application of nicotine salt smoke oil. In the case of ordinary finished large smoke equipment, in addition to excessive power and damage to the smell of smoke, there may be physical discomfort of nicotine overload. What is nicotine salt, Does vladdin contains nicotine salt?
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  9. 2019 New Rules To Prevent Minors From Using E-Cigarettes In USA Schools

    2019 New Rules To Prevent Minors From Using E-Cigarettes In USA Schools

    Schools in the United States are launching a new and stricter program to prevent students from using e-cigarettes in schools and nearby areas. "When students return from spring break, they will be searched to detect if they are using any e-cigarettes," Hamilton school officials announced on March 29. Last year, the U.S. food and drug administration (FDA) launched a series of tough restrictions on companies to prohibit them from selling e-cigarettes to minors. In September 2018, five tobacco manufacturers were required to submit plans to reduce teen use of their products within 60 days. Schools are also taking action to prevent students from vaping. The school’s leaders said they would use handheld metal detectors to randomly search students' lockers and vehicles parked on campus. Once a student is found using the e-cigarette device, he or she will undergo urine analysis within 48 hours. Hamilton School Supervisor Mike Holbrooke said: "After a week's holiday, students will return to school on April 8th, and the search will be started then too." "The students will be randomly checked by specially trained school workers and this will be continued to do." He added: "some students who the staff thinks is suspicious will be targeted." The staff can use the metal detector daily and randomly search for any student. This check can be done at any time and everywhere at school which includes the student's belongings, lockers, vehicles, and other items. The Hamilton School and other schools have launched a campaign to prevent minors from using e-cigarettes locally and even across the United States. It aims at the illegal behavior of some vendors selling e-cigarettes to students. We hereby call for banning the sale of e-cigarettes to minors. Vladdin contains nicotine which is a highly addictive substance. It is not It to sell to non - smokers. What Effect Does Smoking Have On Pregnant Women?
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  10. Health Effects Of E-Cigarettes-From A Study In Hungary

    Health Effects Of E-Cigarettes-From A Study In Hungary

    Health Effects Of E-Cigarettes-From A Study In Hungary In 2015, 1,042 adult Hungarian e-cigarette users were surveyed. To explore the comparison of self-reported adverse events and perceived health changes among Hungarian adult e-cigarette users and dual users (smokers who use e-cigarettes versus conventional cigarettes). Prevalence of vaping-related adverse events and perceived improvement in physiological functions In the survey of adverse events, the number of e-cigarette smokers was 859, accounting for 82.4percent; the number of double smokers was 183, accounting for 17.6percent. As can be seen from the table, the adverse events reported by e-cigarette users only were related to dry mouth and throat, accounting for 3.5percent. Cough and oral cavity were associated with 13.1percent and 6percent of adverse events reported by dual-use subjects. Compared to e-cigarette users, dual users experienced cough, mouth, dizziness, and palpitations. From the table of physiological functions, we can see that about 90percent of e-cigarette users experience better breathing, smell, and taste. About half of e-cigarette users have improved mood, sleep quality and appetite. For the investigation of physiological function, the possibility of improving the health experience of e-cigarette users is significantly higher than that of double users. Perceived improvement in physiological functions in e-cigarette-only users and dual users: binary logistic regression analyses A series of binary logistic regression analyses were performed to compare the health improvement rates of the two types of users. E-cigarette users were more than three times more likely to have improved smell, breathing, taste and endurance than double smokers. They were also twice as likely to report physical conditions, mood and sleep quality. There was no significant difference in the rate of improvement in appetite, sexual ability and memory between e-cigarette users and dual users. found Our study found that only e-cigarette users reported improved health and reduced health impact on vaping compared to two users. Most users who only used e-cigarettes reported better breathing and sensory function and reported only minor adverse events since they started using e-cigarettes. Compared with traditional cigarettes, both smell and taste function are better. Low exposure to potentially toxic substances in e-cigarettes may have a similar but perhaps weaker effect on olfactory mucosa. Improved breathing, general physical condition , and endurance were associated with past smoking habits and duration of e-cigarette use. The most common improvement in these physiologic functions was respiration, is in line with a study in the Netherlands. 90percent of them have better breathing. Users of e-cigarettes alone experienced significant improvements in their mental health. They reported greater improvements in mood and sleep quality. Because they think these e-cigarettes are the same attractive with traditional cigarettes and are a less harmful alternative to it. Improved emotional and psychological quality of life and perceived better respiratory function may explain positive changes in sleep quality. In our analysis, we also identified three major areas of perceived health improvement attributable to e-cigarette use. Sensory improvements include improvements in smell and taste. Improvements in body function include improved breathing, physical health, and increased endurance. Finally, mental health improvement factors include improved appetite, sex life, mood, memory, and sleep. We also noted that dual-users reported much less improvement across all three dimensions than users who only used e-cigarettes. This result suggests that more significant health improvements are associated with complete cessation of regular smoking. The longer the e-cigarette was used, the higher the score of sensory improvement and physical function. Interestingly, smoking intensity before e-cigarette use was also associated with improved sensory and physical function dimensions, suggesting that heavy smokers may have more benefit from switching from combustible cigarettes to e-cigarettes than light smokers. Adverse events, oral and throat discomfort. The use of glycerin, propylene glycol - glycol, and electronic liquid flavoring agents may form during the steam generation process as thermal degradation by-products, which can also be tongue and/or oral pain and oral and throat irritation. Finally, inhalation of e-smoke sol elements such as silicon, sulfur, calcium, titanium, and lithium is associated with throat irritation. Why Your Throat is Uncomfortable While Vaping? conclusion In summary, our study concluded that most users who used e-cigarettes alone reported more beneficial perceived physiological function and that adverse event were less frequent than among dual users. However, despite the uncertainty of long-term health consequences, the short-term benefits of e-cigarette use could strengthen users. But e-cigarettes are not without their negative health consequences. The effects of e-cigarettes on the body will take a long time to study and investigate. Minors under the age of 18 are prohibited from smoking. reference:https://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-019-6629-0#Tab2 2019 What Does A Heavy Smoker Think Of E-Cigarette; 4 Data Show That Vaping Is Safer Than Smoking; Is It Safe To Use Vladdin?
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